As you can imagine, cigarette smoke contains many impurities that are inhaled in great numbers directly into the lung. For this reason, the alveolar spaces of the smoker contain numerous scavenger cells (macrophages) that are filled with engulfed (phagocytized) particles of impurities and debris, as illustrated in Picture of scavenger cells in a smoker's alveolus Under the microscope, with this high magnification, you can actually see the black and brown engulfed particles in the alveolar scavenger cells. Indeed, smoker's lung may have so much of this particulate material that the lung looks gray-black to the naked eye. Most of the time, you don't need a microscope to tell if someone is or was a heavy smoker. A naked eye examination of a smoker's lung will usually reveal an enlarged gray-black lung with enlarged air spaces (the emphysema, as you saw in Figure 4 and will see again in Figure 8).
In the fall of 2011 the Sanofi Pasteur plant flooded causing problems with mold.  The facility, located in Toronto, Ontario, Canada, produced BCG vaccine products, made with the Glaxo 1077 strain,  such as a tuberculosis vaccine ImmuCYST, a BCG Immunotherapeutic -a bladder cancer drug. By April 2012 the FDA had found dozens of documented problems with sterility at the plant including mold, nesting birds and rusted electrical conduits.  The resulting closure of the plant for over two years resulting in shortages of bladder cancer and tuberculosis vaccines.  The Toronto Sanofi plant  On October 29, 2014 Health Canada gave the permission for Sanofi to resume production of BCG. 
After I had eaten the small portion which sufficed to fill my stomach halfway, Brother David casually mentioned his belief that it was an offense against God to leave food uneaten on the table. This was particularly the case when such a great restaurant had so clearly been placed in our path as a special grace. David was a slim man and a monk, so I found it hardly credible that he followed this precept generally. But he continued to eat so much that I felt good manners, if not actual spiritual guidance, required me to imitate his example. I filled my belly for the first time in a year.